However, there haven’t been well designed studies to directly compare the medications, until now, that is.
It was just announced that Shire will be running two different randomized, double blind, placebo controlled trials to compare the two medications: Vyvanse vs. Concerta. The studies will enroll approximately 1000 patients. One study will be a dose optimization study, and one will be forced dose titration. The results are expected in the second half of 2013.
This is exciting from the perspective of understanding the relative benefits of these two top ADHD medications. It is somewhat ‘risky’, from the perspective that Shire is funding this, and they are the makers of Vyvanse. In a study like this, if the data show that Concerta works better than Vyvanse, the data will still be published and released – i.e. a company cannot hide the results of a study at this point in time.
It will be interesting to watch what will happen coming out of this study.
Here is a link to the news story summarizing this issue.